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anota

This is the development version of anota; for the stable release version, see anota.

ANalysis Of Translational Activity (ANOTA).

Bioconductor version: Development (3.18)

Genome wide studies of translational control is emerging as a tool to study verious biological conditions. The output from such analysis is both the mRNA level (e.g. cytosolic mRNA level) and the levl of mRNA actively involved in translation (the actively translating mRNA level) for each mRNA. The standard analysis of such data strives towards identifying differential translational between two or more sample classes - i.e. differences in actively translated mRNA levels that are independent of underlying differences in cytosolic mRNA levels. This package allows for such analysis using partial variances and the random variance model. As 10s of thousands of mRNAs are analyzed in parallell the library performs a number of tests to assure that the data set is suitable for such analysis.

Author: Ola Larsson <ola.larsson at ki.se>, Nahum Sonenberg <nahum.sonenberg at mcgill.ca>, Robert Nadon <robert.nadon at mcgill.ca>

Maintainer: Ola Larsson <ola.larsson at ki.se>

Citation (from within R, enter citation("anota")):

Installation

To install this package, start R (version "4.3") and enter: 

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("anota")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("anota")
ANalysis Of Translational Activity (anota) PDF R Script
Reference Manual PDF
NEWS Text

Details

biocViews DifferentialExpression, GeneExpression, Microarray, Sequencing, Software
Version 1.49.0
In Bioconductor since BioC 2.8 (R-2.13) (12.5 years)
License GPL-3
Depends qvalue
Imports multtest, qvalue
Linking To
Suggests
System Requirements
Enhances
URL
See More
Depends On Me tRanslatome
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package anota_1.49.0.tar.gz
Windows Binary anota_1.49.0.zip
macOS Binary (x86_64) anota_1.49.0.tgz
macOS Binary (arm64) anota_1.49.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/anota
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/anota
Bioc Package Browser https://code.bioconductor.org/browse/anota/
Package Short Url https://bioconductor.org/packages/anota/
Package Downloads Report Download Stats