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DominoEffect

Identification and Annotation of Protein Hotspot Residues

Bioconductor version: Release (3.17)

The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.

Author: Marija Buljan and Peter Blattmann

Maintainer: Marija Buljan <marija.buljan.2 at gmail.com>, Peter Blattmann <peter_blattmann at bluewin.ch>

Citation (from within R, enter citation("DominoEffect")):

Installation

To install this package, start R (version "4.3") and enter: 

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DominoEffect")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("DominoEffect")
Vignette for DominoEffect package HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews Alignment, Proteomics, SequenceMatching, Software, SomaticMutation
Version 1.20.1
In Bioconductor since BioC 3.7 (R-3.5) (5.5 years)
License GPL (>= 3)
Depends R (>= 3.5)
Imports biomaRt, data.table, utils, stats, Biostrings, SummarizedExperiment, VariantAnnotation, AnnotationDbi, GenomeInfoDb, IRanges, GenomicRanges, methods
Linking To
Suggests knitr, testthat, rmarkdown
System Requirements
Enhances
URL
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Depends On Me
Imports Me
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package DominoEffect_1.20.1.tar.gz
Windows Binary DominoEffect_1.20.1.zip (64-bit only)
macOS Binary (x86_64) DominoEffect_1.20.1.tgz
macOS Binary (arm64) DominoEffect_1.20.1.tgz
Source Repository git clone https://git.bioconductor.org/packages/DominoEffect
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/DominoEffect
Bioc Package Browser https://code.bioconductor.org/browse/DominoEffect/
Package Short Url https://bioconductor.org/packages/DominoEffect/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.17 Source Archive