DriverNet
Drivernet: uncovering somatic driver mutations modulating transcriptional networks in cancer
Bioconductor version: Release (3.17)
DriverNet is a package to predict functional important driver genes in cancer by integrating genome data (mutation and copy number variation data) and transcriptome data (gene expression data). The different kinds of data are combined by an influence graph, which is a gene-gene interaction network deduced from pathway data. A greedy algorithm is used to find the possible driver genes, which may mutated in a larger number of patients and these mutations will push the gene expression values of the connected genes to some extreme values.
Author: Ali Bashashati, Reza Haffari, Jiarui Ding, Gavin Ha, Kenneth Liu, Jamie Rosner and Sohrab Shah
Maintainer: Jiarui Ding <jiaruid at cs.ubc.ca>
citation("DriverNet")):
Installation
To install this package, start R (version "4.3") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("DriverNet")For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("DriverNet")| An introduction to DriverNet | R Script | |
| Reference Manual |
Details
| biocViews | Network, Software |
| Version | 1.40.0 |
| In Bioconductor since | BioC 2.12 (R-3.0) (10.5 years) |
| License | GPL-3 |
| Depends | R (>= 2.10), methods |
| Imports | |
| Linking To | |
| Suggests | |
| System Requirements | |
| Enhances | |
| URL |
See More
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | DriverNet_1.40.0.tar.gz |
| Windows Binary | DriverNet_1.40.0.zip |
| macOS Binary (x86_64) | DriverNet_1.40.0.tgz |
| macOS Binary (arm64) | DriverNet_1.40.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/DriverNet |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/DriverNet |
| Bioc Package Browser | https://code.bioconductor.org/browse/DriverNet/ |
| Package Short Url | https://bioconductor.org/packages/DriverNet/ |
| Package Downloads Report | Download Stats |