OUTRIDER
OUTRIDER - OUTlier in RNA-Seq fInDER
Bioconductor version: Release (3.17)
Identification of aberrant gene expression in RNA-seq data. Read count expectations are modeled by an autoencoder to control for confounders in the data. Given these expectations, the RNA-seq read counts are assumed to follow a negative binomial distribution with a gene-specific dispersion. Outliers are then identified as read counts that significantly deviate from this distribution. Furthermore, OUTRIDER provides useful plotting functions to analyze and visualize the results.
Author: Felix Brechtmann [aut], Christian Mertes [aut, cre] 
, Agne Matuseviciute [aut], Michaela Fee Müller [ctb], Vicente Yepez [aut], Julien Gagneur [aut]
Maintainer: Christian Mertes <mertes at in.tum.de>
citation("OUTRIDER")):
Installation
To install this package, start R (version "4.3") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("OUTRIDER")For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("OUTRIDER")| OUTRIDER: OUTlier in RNA-seq fInDER | R Script | |
| Reference Manual | ||
| NEWS | Text | |
| LICENSE | Text |
Details
| biocViews | Alignment, GeneExpression, Genetics, ImmunoOncology, RNASeq, Sequencing, Software, Transcriptomics |
| Version | 1.18.1 |
| In Bioconductor since | BioC 3.8 (R-3.5) (5 years) |
| License | MIT + file LICENSE |
| Depends | R (>= 3.6), BiocParallel, GenomicFeatures, SummarizedExperiment, data.table, methods |
| Imports | BBmisc, BiocGenerics, DESeq2(>= 1.16.1), generics, GenomicRanges, ggplot2, grDevices, heatmaply, pheatmap, graphics, IRanges, matrixStats, plotly, plyr, pcaMethods, PRROC, RColorBrewer, reshape2, S4Vectors, scales, splines, stats, utils |
| Linking To | Rcpp, RcppArmadillo |
| Suggests | testthat, knitr, rmarkdown, BiocStyle, TxDb.Hsapiens.UCSC.hg19.knownGene, org.Hs.eg.db, RMariaDB, AnnotationDbi, beeswarm, covr |
| System Requirements | |
| Enhances | |
| URL | https://github.com/gagneurlab/OUTRIDER |
See More
| Depends On Me | |
| Imports Me | FRASER |
| Suggests Me | |
| Links To Me | |
| Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | OUTRIDER_1.18.1.tar.gz |
| Windows Binary | OUTRIDER_1.18.1.zip |
| macOS Binary (x86_64) | OUTRIDER_1.18.1.tgz |
| macOS Binary (arm64) | OUTRIDER_1.18.1.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/OUTRIDER |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/OUTRIDER |
| Bioc Package Browser | https://code.bioconductor.org/browse/OUTRIDER/ |
| Package Short Url | https://bioconductor.org/packages/OUTRIDER/ |
| Package Downloads Report | Download Stats |
| Old Source Packages for BioC 3.17 | Source Archive |