TargetScore
TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information
Bioconductor version: Release (3.17)
Infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores. Variaitonal Bayesian Gaussian mixture model (VB-GMM) is applied to log fold-changes and sequence scores to obtain the posteriors of latent variable being the miRNA targets. The final targetScore is computed as the sigmoid-transformed fold-change weighted by the averaged posteriors of target components over all of the features.
Author: Yue Li
Maintainer: Yue Li <yueli at cs.toronto.edu>
citation("TargetScore")):
Installation
To install this package, start R (version "4.3") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("TargetScore")For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("TargetScore")| TargetScore: Infer microRNA targets using microRNA-overexpression data and sequence information | R Script | |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | Software, miRNA |
| Version | 1.38.0 |
| In Bioconductor since | BioC 2.13 (R-3.0) (10 years) |
| License | GPL-2 |
| Depends | pracma, Matrix |
| Imports | |
| Linking To | |
| Suggests | TargetScoreData, gplots, Biobase, GEOquery |
| System Requirements | |
| Enhances | |
| URL | http://www.cs.utoronto.ca/~yueli/software.html |
See More
| Depends On Me | |
| Imports Me | |
| Suggests Me | TargetScoreData |
| Links To Me | |
| Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | TargetScore_1.38.0.tar.gz |
| Windows Binary | TargetScore_1.38.0.zip |
| macOS Binary (x86_64) | TargetScore_1.38.0.tgz |
| macOS Binary (arm64) | TargetScore_1.38.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/TargetScore |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/TargetScore |
| Bioc Package Browser | https://code.bioconductor.org/browse/TargetScore/ |
| Package Short Url | https://bioconductor.org/packages/TargetScore/ |
| Package Downloads Report | Download Stats |