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discordant

The Discordant Method: A Novel Approach for Differential Correlation

Bioconductor version: Release (3.17)

Discordant is an R package that identifies pairs of features that correlate differently between phenotypic groups, with application to -omics data sets. Discordant uses a mixture model that “bins” molecular feature pairs based on their type of coexpression or coabbundance. Algorithm is explained further in "Differential Correlation for Sequencing Data"" (Siska et al. 2016).

Author: Charlotte Siska [aut], McGrath Max [aut, cre], Katerina Kechris [aut, cph, ths]

Maintainer: McGrath Max <max.mcgrath at ucdenver.edu>

Citation (from within R, enter citation("discordant")):

Installation

To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("discordant")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("discordant")
The discordant R Package: A Novel Approach to Differential Correlation HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews BiologicalQuestion, Genetics, ImmunoOncology, Microarray, RNASeq, Software, StatisticalMethod, mRNAMicroarray
Version 1.24.0
In Bioconductor since BioC 3.5 (R-3.4) (6.5 years)
License GPL-3
Depends R (>= 4.1.0)
Imports Rcpp, Biobase, stats, biwt, gtools, MASS, tools, dplyr, methods, utils
Linking To Rcpp
Suggests BiocStyle, knitr, testthat (>= 3.0.0)
System Requirements
Enhances
URL https://github.com/siskac/discordant
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package discordant_1.24.0.tar.gz
Windows Binary discordant_1.24.0.zip (64-bit only)
macOS Binary (x86_64) discordant_1.24.0.tgz
macOS Binary (arm64) discordant_1.24.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/discordant
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/discordant
Bioc Package Browser https://code.bioconductor.org/browse/discordant/
Package Short Url https://bioconductor.org/packages/discordant/
Package Downloads Report Download Stats