regutools
regutools: an R package for data extraction from RegulonDB
Bioconductor version: Release (3.17)
RegulonDB has collected, harmonized and centralized data from hundreds of experiments for nearly two decades and is considered a point of reference for transcriptional regulation in Escherichia coli K12. Here, we present the regutools R package to facilitate programmatic access to RegulonDB data in computational biology. regutools provides researchers with the possibility of writing reproducible workflows with automated queries to RegulonDB. The regutools package serves as a bridge between RegulonDB data and the Bioconductor ecosystem by reusing the data structures and statistical methods powered by other Bioconductor packages. We demonstrate the integration of regutools with Bioconductor by analyzing transcription factor DNA binding sites and transcriptional regulatory networks from RegulonDB. We anticipate that regutools will serve as a useful building block in our progress to further our understanding of gene regulatory networks.
Author: Joselyn Chavez [aut, cre] 
, Carmina Barberena-Jonas [aut] , Jesus E. Sotelo-Fonseca [aut] , Jose Alquicira-Hernandez [ctb] , Heladia Salgado [ctb] , Leonardo Collado-Torres [aut] , Alejandro Reyes [aut]
Maintainer: Joselyn Chavez <joselynchavezf at gmail.com>
citation("regutools")):
Installation
To install this package, start R (version "4.3") and enter:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("regutools")For older versions of R, please refer to the appropriate Bioconductor release.
Documentation
To view documentation for the version of this package installed in your system, start R and enter:
browseVignettes("regutools")| regutools: an R package for data extraction from RegulonDB | HTML | R Script |
| Reference Manual | ||
| NEWS | Text |
Details
| biocViews | GeneExpression, GeneRegulation, Network, NetworkInference, Software, SystemsBiology, Transcription, Visualization |
| Version | 1.12.0 |
| In Bioconductor since | BioC 3.11 (R-4.0) (3.5 years) |
| License | Artistic-2.0 |
| Depends | R (>= 4.0) |
| Imports | AnnotationDbi, AnnotationHub, Biostrings, DBI, GenomicRanges, Gviz, IRanges, RCy3, RSQLite, S4Vectors, methods, stats, utils, BiocFileCache |
| Linking To | |
| Suggests | BiocStyle, knitr, RefManageR, rmarkdown, sessioninfo, testthat (>= 2.1.0), covr |
| System Requirements | |
| Enhances | |
| URL | https://github.com/ComunidadBioInfo/regutools |
| Bug Reports | https://support.bioconductor.org/t/regutools |
See More
| Depends On Me | |
| Imports Me | |
| Suggests Me | |
| Links To Me | |
| Build Report |
Package Archives
Follow Installation instructions to use this package in your R session.
| Source Package | regutools_1.12.0.tar.gz |
| Windows Binary | regutools_1.12.0.zip |
| macOS Binary (x86_64) | regutools_1.12.0.tgz |
| macOS Binary (arm64) | regutools_1.12.0.tgz |
| Source Repository | git clone https://git.bioconductor.org/packages/regutools |
| Source Repository (Developer Access) | git clone git@git.bioconductor.org:packages/regutools |
| Bioc Package Browser | https://code.bioconductor.org/browse/regutools/ |
| Package Short Url | https://bioconductor.org/packages/regutools/ |
| Package Downloads Report | Download Stats |