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CDI

This is the development version of CDI; to use it, please install the devel version of Bioconductor.

Clustering Deviation Index (CDI)

Bioconductor version: Development (3.18)

Single-cell RNA-sequencing (scRNA-seq) is widely used to explore cellular variation. The analysis of scRNA-seq data often starts from clustering cells into subpopulations. This initial step has a high impact on downstream analyses, and hence it is important to be accurate. However, there have not been unsupervised metric designed for scRNA-seq to evaluate clustering performance. Hence, we propose clustering deviation index (CDI), an unsupervised metric based on the modeling of scRNA-seq UMI counts to evaluate clustering of cells.

Author: Jiyuan Fang [cre, aut] , Jichun Xie [ctb], Cliburn Chan [ctb], Kouros Owzar [ctb], Liuyang Wang [ctb], Diyuan Qin [ctb], Qi-Jing Li [ctb], Jichun Xie [ctb]

Maintainer: Jiyuan Fang <jfanglovestats at gmail.com>

Citation (from within R, enter citation("CDI")):

Installation

To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("CDI")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews CellBasedAssays, Clustering, RNASeq, Sequencing, SingleCell, Software, Visualization
Version 0.99.21
In Bioconductor since BioC 3.18 (R-4.3)
License GPL-3 + file LICENSE
Depends R (>= 3.6)
Imports matrixStats, Seurat, SeuratObject, stats, BiocParallel, ggplot2, reshape2, grDevices, ggsci, SingleCellExperiment, SummarizedExperiment, methods
Linking To
Suggests knitr, rmarkdown, RUnit, BiocGenerics, magick
System Requirements
Enhances
URL https://github.com/jichunxie/CDI
Bug Reports https://github.com/jichunxie/CDI/issues
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary CDI_0.99.21.zip
macOS Binary (x86_64) CDI_0.99.21.tgz
macOS Binary (arm64) CDI_0.99.21.tgz
Source Repository git clone https://git.bioconductor.org/packages/CDI
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/CDI
Bioc Package Browser https://code.bioconductor.org/browse/CDI/
Package Short Url https://bioconductor.org/packages/CDI/
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