This site is a development preview. As such the content and styling may not be final and is subject to change before going into production. To see more information about the redesign click here.

MPO.db

This is the development version of MPO.db; to use it, please install the devel version of Bioconductor.

A set of annotation maps describing the Mouse Phenotype Ontology

Bioconductor version: Development (3.18)

We have developed the human disease ontology R package HDO.db, which provides the semantic relationship between human diseases. Relying on the DOSE and GOSemSim packages we developed, we can carry out disease enrichment and semantic similarity analyses. Many biological studies are achieved through mouse models, and a large number of data indicate the association between genotypes and phenotypes or diseases. The study of model organisms can be transformed into useful knowledge about normal human biology and disease to facilitate treatment and early screening for diseases. Organism-specific genotype-phenotypic associations can be applied to cross-species phenotypic studies to clarify previously unknown phenotypic connections in other species. Using the same principle to diseases can identify genetic associations and even help to identify disease associations that are not obvious. Therefore, as a supplement to HDO.db and DOSE, we developed mouse phenotypic ontology R package MPO.db.

Author: Erqiang Hu [aut, cre]

Maintainer: Erqiang Hu <13766876214 at 163.com>

Citation (from within R, enter citation("MPO.db")):

Installation

To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("MPO.db")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("MPO.db")
MPO_vignette HTML R Script
Reference Manual PDF
NEWS Text

Details

biocViews AnnotationData, AnnotationHub, FunctionalAnnotation
Version 0.99.7
License Artistic-2.0
Depends R (>= 4.3.0)
Imports AnnotationDbi, AnnotationHub, BiocFileCache, DBI, methods, utils
Linking To
Suggests rmarkdown, knitr, testthat (>= 3.0.0)
System Requirements
Enhances
URL https://github.com/YuLab-SMU/MPO.db
Bug Reports https://github.com/YuLab-SMU/MPO.db/issues
See More
Depends On Me
Imports Me DOSE
Suggests Me
Links To Me

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package MPO.db_0.99.7.tar.gz
Windows Binary
macOS Binary (x86_64)
macOS Binary (arm64)
Package Short Url https://bioconductor.org/packages/MPO.db/
Package Downloads Report Download Stats