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les

Identifying Differential Effects in Tiling Microarray Data

Bioconductor version: Release (3.17)

The 'les' package estimates Loci of Enhanced Significance (LES) in tiling microarray data. These are regions of regulation such as found in differential transcription, CHiP-chip, or DNA modification analysis. The package provides a universal framework suitable for identifying differential effects in tiling microarray data sets, and is independent of the underlying statistics at the level of single probes.

Author: Julian Gehring, Clemens Kreutz, Jens Timmer

Maintainer: Julian Gehring <jg-bioc at gmx.com>

Citation (from within R, enter citation("les")):

Installation

To install this package, start R (version "4.3") and enter: 

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("les")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("les")
Introduction to the les package: Identifying Differential Effects in Tiling Microarray Data with the Loci of Enhanced Significance Framework PDF R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews ChIPchip, DNAMethylation, DifferentialExpression, Microarray, Software, Transcription
Version 1.50.0
In Bioconductor since BioC 2.7 (R-2.12) (13 years)
License GPL-3
Depends R (>= 2.13.2), methods, graphics, fdrtool
Imports boot, gplots, RColorBrewer
Linking To
Suggests Biobase, limma
System Requirements
Enhances parallel
URL
See More
Depends On Me
Imports Me GSRI
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package les_1.50.0.tar.gz
Windows Binary les_1.50.0.zip
macOS Binary (x86_64) les_1.50.0.tgz
macOS Binary (arm64) les_1.50.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/les
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/les
Bioc Package Browser https://code.bioconductor.org/browse/les/
Package Short Url https://bioconductor.org/packages/les/
Package Downloads Report Download Stats