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limma

Linear Models for Microarray Data

Bioconductor version: Release (3.17)

Data analysis, linear models and differential expression for microarray data.

Author: Gordon Smyth [cre,aut], Yifang Hu [ctb], Matthew Ritchie [ctb], Jeremy Silver [ctb], James Wettenhall [ctb], Davis McCarthy [ctb], Di Wu [ctb], Wei Shi [ctb], Belinda Phipson [ctb], Aaron Lun [ctb], Natalie Thorne [ctb], Alicia Oshlack [ctb], Carolyn de Graaf [ctb], Yunshun Chen [ctb], Mette Langaas [ctb], Egil Ferkingstad [ctb], Marcus Davy [ctb], Francois Pepin [ctb], Dongseok Choi [ctb]

Maintainer: Gordon Smyth <smyth at wehi.edu.au>

Citation (from within R, enter citation("limma")):

Installation

To install this package, start R (version "4.3") and enter:

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("limma")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("limma")
Limma One Page Introduction PDF
usersguide.pdf PDF
Reference Manual PDF
NEWS Text

Details

biocViews AlternativeSplicing, BatchEffect, Bayesian, BiomedicalInformatics, CellBiology, Cheminformatics, Clustering, DataImport, DifferentialExpression, DifferentialSplicing, Epigenetics, ExonArray, FunctionalGenomics, GeneExpression, GeneSetEnrichment, Genetics, ImmunoOncology, Metabolomics, MicroRNAArray, Microarray, MultipleComparison, Normalization, OneChannel, Preprocessing, ProprietaryPlatforms, Proteomics, QualityControl, RNASeq, Regression, Sequencing, Software, SystemsBiology, TimeCourse, Transcription, Transcriptomics, TwoChannel, mRNAMicroarray
Version 3.56.2
In Bioconductor since BioC 1.6 (R-2.1) or earlier (> 18 years)
License GPL (>=2)
Depends R (>= 3.6.0)
Imports grDevices, graphics, stats, utils, methods
Linking To
Suggests affy, AnnotationDbi, BiasedUrn, Biobase, ellipse, GO.db, gplots, illuminaio, locfit, MASS, org.Hs.eg.db, splines, statmod (>= 1.2.2), vsn
System Requirements
Enhances
URL https://bioinf.wehi.edu.au/limma/
See More
Depends On Me AgiMicroRna, ASpli, BLMA, CCl4, cghMCR, ChimpHumanBrainData, clippda, codelink, convert, Cormotif, deco, DEqMS, DrugVsDisease, edgeR, EGSEA123, ExiMiR, ExpressionAtlas, Fletcher2013a, GEOexplorer, HD2013SGI, HTqPCR, IsoformSwitchAnalyzeR, maEndToEnd, maigesPack, maPredictDSC, marray, metagenomeSeq, metaseqR2, methylationArrayAnalysis, mpra, NanoTube, NeuCA, octad, protGear, qpcrNorm, qusage, RBM, ReactomeGSA.data, Ringo, RNAseq123, RnBeads, Rnits, splineTimeR, TOAST, tRanslatome, TurboNorm, variancePartition, wateRmelon, zenith
Imports Me a4Base, ABSSeq, affycoretools, affylmGUI, AMARETTO, animalcules, anota2seq, ArrayExpress, arrayQuality, arrayQualityMetrics, artMS, ASpediaFI, ATACseqQC, ATACseqTFEA, attract, autonomics, AWFisher, ballgown, BatchQC, beadarray, BeadArrayUseCases, benchdamic, biotmle, BloodGen3Module, bnem, bsseq, BubbleTree, bumphunter, CancerSubtypes, casper, ChAMP, ChIPComp, clusterExperiment, CNVRanger, combi, compcodeR, CONFESS, consensusDE, consensusOV, crlmm, crossmeta, csaw, cTRAP, ctsGE, DAMEfinder, DaMiRseq, debrowser, DELocal, DEP, derfinderPlot, DESpace, DEsubs, DExMA, DiffBind, diffcyt, diffHic, diffUTR, distinct, DmelSGI, DMRcate, Doscheda, DRIMSeq, eegc, EGAD, EGSEA, eisaR, EnrichmentBrowser, epigraHMM, EpiMix, erccdashboard, EventPointer, EWCE, ExpHunterSuite, ExploreModelMatrix, ExpressionNormalizationWorkflow, extraChIPs, flowBin, gCrisprTools, GDCRNATools, genefu, GeneSelectMMD, GEOquery, Glimma, GOsummaries, GRaNIE, GUIDEseq, GWAS.BAYES, hermes, hipathia, HTqPCR, icetea, iCheck, iChip, iCOBRA, ideal, InPAS, isomiRs, KnowSeq, limmaGUI, Linnorm, lipidr, lmdme, mAPKL, mastR, MatrixQCvis, MBECS, MBQN, mCSEA, MEAL, methylKit, MethylMix, microbiomeExplorer, microbiomeMarker, MIGSA, miloR, minfi, miRLAB, missMethyl, MLSeq, moanin, monocle, MoonlightR, msImpute, msqrob2, MSstats, MSstatsTMT, MultiDataSet, muscat, NADfinder, NanoMethViz, nethet, nondetects, NormalyzerDE, OLIN, omicRexposome, oppti, OVESEG, PAA, PADOG, pairedGSEA, PanomiR, PathoStat, pcaExplorer, PECA, pepStat, phantasus, phenomis, phenoTest, PhosR, polyester, POMA, POWSC, projectR, psichomics, pwrEWAS, qmtools, qPLEXanalyzer, qsea, rCGH, recountWorkflow, RegEnrich, regsplice, ReportingTools, Ringo, RNAinteract, ROSeq, RTN, RTopper, satuRn, scClassify, scone, scran, ScreenR, scviR, SEPIRA, seqsetvis, shinyepico, signatureSearchData, SimBindProfiles, SingleCellSignalR, singleCellTK, snapCGH, sparrow, spatialLIBD, speckle, SPsimSeq, standR, STATegRa, Statial, sva, timecourse, TOP, ToxicoGx, TPP, TPP2D, transcriptogramer, TVTB, tweeDEseq, vsclust, vsn, weitrix, Wrench, yamss, yarn
Suggests Me ABarray, ADaCGH2, arrays, beadarraySNP, biobroom, BiocSet, BioNet, BioQC, BloodCancerMultiOmics2017, CAGEWorkflow, Category, categoryCompare, celaref, CellBench, CellMixS, ChIPpeakAnno, ClassifyR, CMA, coGPS, CONSTANd, cydar, DAPAR, dearseq, DEGreport, derfinder, DEScan2, dyebias, easyreporting, EnMCB, fgsea, fishpond, fluentGenomics, gage, GeoTcgaData, GeuvadisTranscriptExpr, geva, glmGamPoi, GSRI, GSVA, Harman, Heatplus, isobar, ivygapSE, les, lionessR, lumi, mammaPrintData, MAST, methylumi, MLP, msigdb, npGSEA, NxtIRFcore, oligo, oppar, piano, PREDA, proDA, puma, QFeatures, qsvaR, randRotation, recountmethylation, ribosomeProfilingQC, rtracklayer, seventyGeneData, signifinder, simpleSingleCell, spatialHeatmap, SpliceWiz, stageR, subSeq, SummarizedBenchmark, systemPipeR, TCGAbiolinks, tidybulk, topconfects, tximeta, tximport, ViSEAGO, zFPKM
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package limma_3.56.2.tar.gz
Windows Binary limma_3.56.2.zip (64-bit only)
macOS Binary (x86_64) limma_3.56.2.tgz
macOS Binary (arm64) limma_3.56.2.tgz
Source Repository git clone https://git.bioconductor.org/packages/limma
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/limma
Bioc Package Browser https://code.bioconductor.org/browse/limma/
Package Short Url https://bioconductor.org/packages/limma/
Package Downloads Report Download Stats
Old Source Packages for BioC 3.17 Source Archive