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svaRetro

Retrotransposed transcript detection from structural variants

Bioconductor version: Release (3.17)

svaRetro contains functions for detecting retrotransposed transcripts (RTs) from structural variant calls. It takes structural variant calls in GRanges of breakend notation and identifies RTs by exon-exon junctions and insertion sites. The candidate RTs are reported by events and annotated with information of the inserted transcripts.

Author: Ruining Dong [aut, cre]

Maintainer: Ruining Dong <lnyidrn at gmail.com>

Citation (from within R, enter citation("svaRetro")):

Installation

To install this package, start R (version "4.3") and enter: 

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("svaRetro")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("svaRetro")
svaRetro Package HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews Annotation, Coverage, DataImport, Genetics, Sequencing, Software, VariantAnnotation, VariantDetection
Version 1.6.0
In Bioconductor since BioC 3.14 (R-4.1) (2 years)
License GPL-3 + file LICENSE
Depends GenomicRanges, rtracklayer, BiocGenerics, StructuralVariantAnnotation, R (>= 4.0)
Imports VariantAnnotation, assertthat, Biostrings, stringr, dplyr, methods, rlang, GenomicFeatures, GenomeInfoDb, S4Vectors, utils
Linking To
Suggests TxDb.Hsapiens.UCSC.hg19.knownGene, ggplot2, devtools, testthat (>= 2.1.0), roxygen2, knitr, BiocStyle, plyranges, circlize, tictoc, IRanges, stats, SummarizedExperiment, rmarkdown
System Requirements
Enhances
URL
Bug Reports https://github.com/PapenfussLab/svaRetro/issues
See More
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package svaRetro_1.6.0.tar.gz
Windows Binary svaRetro_1.6.0.zip
macOS Binary (x86_64) svaRetro_1.6.0.tgz
macOS Binary (arm64) svaRetro_1.6.0.tgz
Source Repository git clone https://git.bioconductor.org/packages/svaRetro
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/svaRetro
Bioc Package Browser https://code.bioconductor.org/browse/svaRetro/
Package Short Url https://bioconductor.org/packages/svaRetro/
Package Downloads Report Download Stats